ERYTHROMYCIN LACTOBIONATE

Brand Name & Strength

Erythromycin Lactobionate Injection 500 mg

Reconstitution

Reconstitute with 10 ml WFI (concentration: 50 mg/ml)

Further Dilution

Dilute reconstituted solution with diluent to a final concentration of 1 – 5 mg/ml

Diluent

NS, D5

Administration & Infusion rate

IV infusion

Administer over 20 – 60 min Continuous

IV infusion

Administer daily dose over 6 – 24 hr

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

24 hr 2 weeks

After dilution

8 hr -

Remarks

Do not administer IV push or bolus

Rapid infusion is more likely to be associated with arrhythmias or hypotension

Erythromycin should not be reconstituted with inorganic salt solution. Use only WFI